Alya Red, a project of the Barcelona Supercomputing Center that tries to understand the wondrous organ that is the heart and when the mechanism fails. The simulator generates electrical signals to try and exactly mimic the speed at which the signals propagate across the heart. An attempt to create an accurate electro-mechanical model of a heartbeat all with the help of 10,000 processors.
Oh and while you are at it check out her other site Anatomy UK
Anatomy UK is a site run by Emily to reflect anatomical creativity both in the UK and worldwide. The new exciting creative ideas emerging that have been inspired by anatomy are continually pushing the boundaries of how we perceive it…. it’s no longer just for the academics.
I emphasized that last part. Spread the word. Histology is growing. Heart it.
An eminent philosopher among my friends, who can dignify even your ugly furniture by lifting it into the serene light of science, has shown me this pregnant little fact. Your pier-glass or extensive surface of polished steel made to be rubbed by a housemaid, will be minutely and multitudinously scratched in all directions; but place now against it a lighted candle as a centre of illumination, and lo! the scratches will seem to arrange themselves in a fine series of concentric circles round that little sun. It is demonstrable that the scratches are going everywhere impartially, and it is only your candle which produces the flattering illusion of a concentric arrangement, its light falling with an exclusive optical selection. These things are a parable. The scratches are events, and the candle is the egoism of any person…
This movie shows the “yolk flash”. The apparently whole-embryo calcium pulse appears to initiate over a widespread area of blastoderm, possibly earliest at the animal pole, and then spreads first to the yolk cell membrane and then along the ventral midline heading rostrally. 30-sec integration window moving in 5-sec steps, elapsed real time of 340 sec played at 50x real time.. Fertilized zebrafish eggs were collected within 5 min of spawning, enzymatically dechorionated, and injected with approximately 0.9 nl of a 1% solution of recombinant f-aequorin in 100 mM KCl, 5 mM Mops, and 50 μM EDTA. During imaging the embryos were maintained at 28°C in 30% Danieau’s medium containing penicillin (0.5 mg/ml), streptomycin (5,000 units/ml; Sigma), and 0.5% methylcellulose. Imaging was performed on a Photon Imaging Microscope (Science Wares, Falmouth, MA) that used a photon-counting spatial detector with a resistive anode output (Photek, St. Albens-on-Sea, U.K.). Digitized detector output in the form of a stream of time-labeled eight-bit x—y coordinates (256 × 256 pixels) was used to construct time-lapse imaging sequences. The imaging system software allowed the original photon data stream to be analyzed according to any chosen integration time, with the resulting image frames maintaining accurate photon quantitation up to 256 photons per pixel. These images are part of an image series within the Zebrafish—The Living Laboratory CD made available by Mark Cooper and described in Methods in Cell Biology Volume 77, 2004, Pages 439-457. Corresponds to supplemental video in PNAS January 5, 1999 vol. 96: 157-161 and quantification of color scale shown in Fig 1.